Alexandre Palagi, Ph.D. has experience drafting and prosecuting patent applications, advising in-house counsel on patent prosecution strategies and conducting research to ensure his clients are informed on best practices for patent drafting. His technical focus is in the area of life sciences, in view of his background in biology, molecular biology, genetics and biochemistry.

Specifically, his doctoral research was done as part of a joint program between the University of Nice, Harvard Medical School, and Brigham and Women’s Hospital and was centered around the regulation of gene transcription and expression and genome editing. Primary subjects included genome engineering by CRISPR-Cas9, the study of protein-DNA interaction, and the development and use of highly parallel methods for the discovery of transcriptional enhancers and silencers.

Previously, Mr. Palagi was a visiting graduate student at the Center for Cancer Systems Biology at the Dana-Farber Cancer Institute, where the principal aim of his work was the characterization of the impact on protein-protein interaction of natural non-synonymous Single Nucleotide Polymorphisms (SNPs) present in the human genome. Earlier, he served as a summer intern at the Bulyk Laboratory, which is affiliated with the Department of Medicine at Brigham and Women’s Hospital and Harvard Medical School. He was also a research intern at VenomeTech, where he studied the composition of venoms, as a source of new and potential drug candidates.

    • Transcriptional Silencers in Drosophila Serve a Dual Role as Transcriptional Enhancers in Alternate Cellular Contexts - Molecular Cell, Volume 77, Issue 2 (January 16, 2020)
    • Widespread macromolecular interaction perturbations in human genetic disorders - Cell, Volume 161, Issue 3 (April 23, 2015)
    • Unravelling the complex venom landscapes of lethal Australian funnel-web spiders (Hexathelidae: Atracinae) using LC-MALDI-TOF mass spectrometry - Journal of Proteomics, Volume 80 (March 27, 2013)