Kiruthika Elamparuthi, Ph.D. is a registered patent agent in the patent counseling and prosecution practice of Dechert’s intellectual property life sciences group. Dr. Elamparuthi focuses her practice on chemical and pharmaceutical intellectual property matters, including the drafting and prosecution of patent applications before the U.S. Patent and Trademark Office and foreign patent offices. She leverages her training in organic chemistry to assist and advise clients on a variety of Intellectual Property matters including patent portfolio management strategies, evaluations and opinions on patentability, freedom-to-operate, clearance and transactional due diligence.

Before joining Dechert, Dr. Elamparuthi worked at a global law firm as a patent agent in patent prosecution. Prior to practicing law, Dr. Elamparuthi served as a senior scientist at Venenum Biodesign where she facilitated small molecule drug discovery. Her work focused on early-stage drug discovery, identifying hits, and interpreting structure-activity relationships in addition to addressing ADME challenges for lead generation and optimization by designing and constructing novel drug scaffolds for immune-oncology, infectious diseases and metabolic disorders. This work as a medicinal chemist resulted in Dr. Elamparuthi listed as a co-inventor in patent applications.

Her academic tenure includes a masters and Ph.D in organic chemistry from the University of Madras where her research work focused on methodology development for constructing heterocycles using transition metal catalysis and multi-component reactions involving alkynes. Her work utilized the less-exploited copper-catalyzed cross-coupling reactions of ynamides to develop interesting heterocyclic scaffolds which have extensive applications in medicinal chemistry and material science in an inter/intramolecular one-pot fashion.

    • Kiruthika, S. E., Nandakumar, A. and Perumal, P. T. “Synthesis of Pyrrolo-/Indolo[1,2-a]quinolines and Naphtho[2,1-b]thiophenes from gem-Dibromovinyls and Sulphonamides”, Org. Lett. 2014, 16, 4424–4427.
    • Kiruthika, S. E. and Perumal, P. T. “CuI-Catalyzed Coupling of gem-Dibromovinylanilides and Sulfonamides: An Efficient Method for the Synthesis of 2-Amidoindoles and Indolo[1,2-a]quinazolines”, Org. Lett. 2014, 16, 484-487.
    • Kiruthika, S. E. and Perumal, P. T. “One-pot four-component approach for the construction of dihydropyridines and dihydropyridinones using amines and activated alkynes”, RSC Adv. 2014, 4, 3758-3767.
    • Kiruthika, S. E., Amritha, R. and Perumal, P. T. “An efficient strategy for functionalized spirolactones and dispirodihydrofuranyl oxindoles using amines and activated alkynes”, Tetrahedron. Lett.  2012, 53, 3268-3273.
    • Kiruthika, S. E., Lakshmi, N. V., Banu, B. R. and Perumal, P. T. “A facile strategy for the one pot multicomponent synthesis of spiro dihydropyridines from amines and activated alkynes”, Tetrahedron. Lett. 2011, 52, 6508–6511.
    • Kiruthika, S. E., Nandakumar, A., Naveen, K. and Perumal, P. T. “Pd(0)-catalyzed regio-and stereoselective cyclization of alkynes: selective synthesis of (E)-4-(isobenzofuran-1(3H)-ylidene)-1,2,3,4-tetrahydroisoquinolines and aze/oxepinoindoles.”, Org. Biomol. Chem. 2014, 12, 876-880.
    • Kiruthika S. E., Perumal, P.T., Balachandran, C. and Ignacimuthu, S. “An easy protocol for the domino synthesis of diversely functionalized spirocarbocycles and their biological evaluation”, Journal of Chemical Sciences, 2014, 126, 177-185.
    • Lakshmi, N. V., Kiruthika, S. E. and Perumal, P. T.  “A Rapid and Efficient Access to 4-Substituted 2-Amino-4H-chromenes Catalyzed by InCl3” Synlett,  2011, 10, 1389-1394.
    • Lakshmi, N. V., Kiruthika, S. E. and Perumal, P. T. “Multicomponent assembly of 2-amino-4-substituted 4H-chromenes using cyclic N-Michael donor” Canadian Journal of Chemistry, 2013, 91, 479-485.