Mark S. Cheffo


Mark S. Cheffo


New York | Three Bryant Park, 1095 Avenue of the Americas, New York, NY, United States of America 10036-6797
+1 212 698 3814 | +1 212 698 3599


Mark S. Cheffo is co-chair of Dechert’s product liability and mass torts practice and has extensive experience serving as national coordinating and trial counsel in complex product liability, insurance and mass torts litigation. He acts for corporations and individuals in the pharmaceutical, medical device manufacturing, bioengineering, insurance and industrial products industries, amongst others. Mr. Cheffo has also handled numerous toxic and environmental exposure suits.

Mr. Cheffo has taken part in several trial teams in high-profile pharmaceutical litigation, managing all stages of a dispute from negotiation, through pre-trial proceedings to trial. In addition to defending expert and company witness depositions, Mr. Cheffo has briefed and conducted numerous Daubert and Frye challenges. He has also briefed and argued dispositive motions and appeals in state and federal courts throughout the United States. Mr. Cheffo also has considerable experience conducting arbitrations and mediations relating to disputes.

Widely recognized as a leader in the field, Mr. Cheffo is ranked in Band 1 by Chambers USA for product liability matters. He has also been named as a “Litigator of the Week” by The American Lawyer. In 2019, Mr. Cheffo was selected as one of Law360’s MVPs of the Year in the Product Liability category. He is part of a product liability team that has won numerous accolades over the last two decades and taken lead roles in some of the nation’s most significant and high-profile disputes.

Mr. Cheffo maintains an active pro bono practice, assisting clients in a variety of matters. Most notably, he obtained a judgment of more than US$1.7 million for liability and legal fees on behalf of 11 restaurant workers in New York’s Chinatown. He also obtained a jury verdict in a defamation case and obtained a directed verdict in a case brought by three plaintiffs who had been shot while in prison.

Prior to joining Dechert, Mr. Cheffo was co-chair of Quinn Emanuel Urquhart & Sullivan’s global product liability and mass torts practice.

  • A major pharmaceutical company as national coordinating and trial counsel in nationwide litigation involving several of the company’s leading prescription medications.  
  • Several pharmaceutical companies in securing a complete dismissal in multidistrict litigation in connection with personal injury claims arising from the manufacturing and distribution of generic prescription medications containing propoxyphene.
  • A client in successfully arguing a motion to dismiss a consolidated nationwide consumer fraud class action complaint in an MDL and also argued the appeal in the Ninth Circuit, where the district court’s decision was affirmed.
  • A major biotechnology company in multidistrict litigation involving a nationwide consumer fraud action.
  • Several major pharmaceutical companies in connection with the development of risk management initiatives, labelling advice and document management.  
  • One of the world’s largest computer manufacturers in class actions challenging alleged product defects.
  • Individual and corporate property owners in connection with more than 70 cases alleging pediatric brain injuries from exposure to environmental toxins. 

Includes matters handled at Dechert or prior to joining the firm.

  • Stony Brook University, B.A., with Honors, 1987, Pi Sigma Alpha National Political Science Honor Society, Phi Alpha Theta International History Honor Society
  • Boston University School of Law, J.D., 1990, Editor-in-Chief of American Journal of Law & Medicine, Paul J. Liacos Scholar
  • New York
  • United States Court of Appeals for the First Circuit
  • United States Court of Appeals for the Second Circuit
  • United States Court of Appeals for the Fourth Circuit
  • United States Court of Appeals for the Sixth Circuit
  • United States Court of Appeals for the Ninth Circuit
  • United States District Court for the Eastern District of New York
  • United States District Court for the Southern District of New York
  • New York City Bar Association
  • International Association of Defense Counsel